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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 13.64
Human Site: S403 Identified Species: 20
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S403 S R A L T P P S Y S T A K N S
Chimpanzee Pan troglodytes XP_001153855 674 74011 I344 L G K F V P P I P K Q D G G E
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S403 S R A L T P P S Y S T A K N S
Dog Lupus familis XP_545496 695 74019 E365 Y P S P G V G E P G E E H R P
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S403 S R A L T P P S Y S T A K N S
Rat Rattus norvegicus Q6GX84 677 74178 S347 G K F V P P V S N K Q D G S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 P400 P F G K F I P P V P R S D G G
Chicken Gallus gallus Q5ZK92 613 66247 T283 R P A A N P A T S T H K A A P
Frog Xenopus laevis Q6DDU8 655 72133 F324 S R G L H G K F I P P L P R Q
Zebra Danio Brachydanio rerio Q503S1 736 79183 G399 S L G S M R S G E S F G K F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 L193 M N F R K K T L G G K R T V S
Honey Bee Apis mellifera XP_625184 585 66969 F255 N S Q F V C P F K R E K E K I
Nematode Worm Caenorhab. elegans O16299 594 66169 L264 P K R C S N P L I R K A M G M
Sea Urchin Strong. purpuratus XP_783737 603 65189 G273 E A D N S M G G Y K P P S R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 K193 G K K G A A S K S N K A E S M
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 S494 K K T S S H P S R P V S N S K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 13.3 100 0 N.A. 100 13.3 N.A. 6.6 13.3 20 20 N.A. 6.6 6.6 13.3 6.6
P-Site Similarity: 100 13.3 100 6.6 N.A. 100 33.3 N.A. 13.3 26.6 20 20 N.A. 6.6 20 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 25 7 7 7 7 0 0 0 0 32 7 7 0 % A
% Cys: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 0 0 0 0 0 0 0 13 7 0 0 % D
% Glu: 7 0 0 0 0 0 0 7 7 0 13 7 13 0 13 % E
% Phe: 0 7 13 13 7 0 0 13 0 0 7 0 0 7 0 % F
% Gly: 13 7 19 7 7 7 13 13 7 13 0 7 13 19 13 % G
% His: 0 0 0 0 7 7 0 0 0 0 7 0 7 0 0 % H
% Ile: 0 0 0 0 0 7 0 7 13 0 0 0 0 0 7 % I
% Lys: 7 25 13 7 7 7 7 7 7 19 19 13 25 7 7 % K
% Leu: 7 7 0 25 0 0 0 13 0 0 0 7 0 0 0 % L
% Met: 7 0 0 0 7 7 0 0 0 0 0 0 7 0 13 % M
% Asn: 7 7 0 7 7 7 0 0 7 7 0 0 7 19 7 % N
% Pro: 13 13 0 7 7 38 50 7 13 19 13 7 7 0 13 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 13 0 0 0 7 % Q
% Arg: 7 25 7 7 0 7 0 0 7 13 7 7 0 19 0 % R
% Ser: 32 7 7 13 19 0 13 32 13 25 0 13 7 19 25 % S
% Thr: 0 0 7 0 19 0 7 7 0 7 19 0 7 0 0 % T
% Val: 0 0 0 7 13 7 7 0 7 0 7 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _